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Heartseed

Heartseed株式会社

Company highlights

The largest holder on the register is 福田 惠一, at 13.8%.

Key figures

Period Nov 2024 to Dec 2025Parent onlyJapanese GAAP

RevenueDisclosed ¥3.0B
Operating marginCalculated 9.0%
Net assets to total assetsCalculated 93.7%

Company profile

Securities code 219A / EDINET code E39759 / Pharmaceuticals / Fiscal year end October 31

港区芝浦1丁目2番3号シーバンスS館5階/Capital stock ¥50 million
Address, capital stock, fiscal year end and industry: the FSA’s EDINET code list.

Company details
福田 惠一 Representative

Tables scroll sideways

Disclosed data

Source: Annual Securities Report (Nov 2024 to Dec 2025) · filed 2026-03-26

Profitability ★★★★☆position among all companies 9.0%
Growth (revenue, 4-year average) ★★★★★position among all companies 16.6%
Capital efficiency Could not be retrieved

Business activities and revenue composition

Revenue and profit by business segment

Disclosed segments (business divisions used in reporting): one

Revenue and profit

Amounts by account
GroupAccountAmountConsolidated / Non-consolidated
Selling, general and administrative expenses Research and development expenses ¥2.0 billion Parent only
Directors' compensations ¥0.2 billion Parent only
Salaries and allowances ¥0.1 billion Parent only
Commission fees ¥0.1 billion Parent only
Depreciation ¥7.81 million Parent only
Profit by stage Gross profit (loss) ¥3.0 billion Parent only
Ordinary income ¥0.3 billion Parent only
Operating income ¥0.3 billion Parent only

Heartseed

Selling, general and administrative expenses

Period Nov 2024 to Dec 2025Source Annual securities reports

Research and development expenses ¥2.0 billion (80.7%)81%Directors' compensations ¥0.2 billion (7.3%)7%Salaries and allowances ¥0.1 billion (5.9%)Commission fees ¥0.1 billion (5.8%)Depreciation ¥0.0 billion (0.3%)¥2.5B
  • Research and development expenses ¥2.0 billion
  • Directors' compensations ¥0.2 billion
  • Salaries and allowances ¥0.1 billion
  • Commission fees ¥0.1 billion
  • Depreciation ¥0.0 billion

Performance, financial position and capital allocation

Finance
93.7% Net assets to total assets Industry median 69.7% FY ending 12/2025 · consolidated / calculated
¥314.56 Net assets per share
¥7.7 billion Total assets
Capital allocation
396.7% Cash conversion Industry median 112.1% FY ending 12/2025 · consolidated / calculated

Heartseed

Recent performance trends

Source Annual securities reports

3 2 0 -1 4 years ago 3 years ago 2 years ago Last year This year Net sales and operating revenue Ordinary income ¥ billion

Year-on-year comparison

Period 2021 to 2025Disclosed

Item20212022202320242025
Net sales ¥1.6B ¥0.5B ¥0.3B ¥0.9B ¥3.0B
Year on year (%) Could not be retrieved -69.5%◆ -30.9%◆ +153.4%◆ comparison basis not confirmed
Ordinary income (loss) -¥0.3B -¥1.4B -¥1.5B -¥0.8B ¥0.3B
Change from prior year Could not be retrieved 5.52x 1.03x 0.56x comparison basis not confirmed
Ordinary income (loss) as a share of Net sales -15.6% -282.6% -422.5% -93.7% 9.5%
Change (percentage points) Could not be retrieved -267.0 points◆ -139.9 points◆ +328.8 points◆ comparison basis not confirmed

Fiscal periods marked for changes

  • 2022Net sales year on year -69.5%, Ordinary income (loss) as a share of revenue -267.0 points
  • 2023Net sales year on year -30.9%, Ordinary income (loss) as a share of revenue -139.9 points
  • 2024Net sales year on year +153.4%, Ordinary income (loss) as a share of revenue +328.8 points

Heartseed

Earnings and net assets per share over time

Unit yenSource Annual securities reports

8 -6,294 -12,597 -18,900 4 years ago 3 years ago 2 years ago Last year This year Earnings per share yen 315 -23,731 -47,776 -71,821 4 years ago 3 years ago 2 years ago Last year This year Net assets per share yen
Parent only indicators (16 items)
Item4 years ago3 years ago2 years agoLast yearThis year
Net sales ¥1.6 billion ¥0.5 billion ¥0.3 billion ¥0.9 billion ¥3.0 billion
Ordinary income (loss) ¥-0.3 billion ¥-1.4 billion ¥-1.5 billion ¥-0.8 billion ¥0.3 billion
Net income (loss) ¥-0.3 billion ¥-1.4 billion ¥-1.5 billion ¥-0.8 billion ¥0.2 billion
Capital stock ¥50.00 million ¥50.00 million ¥50.00 million ¥1.1 billion ¥1.3 billion
Total number of issued shares (common stock) 13,690 shares 13,690 shares 10,952,000 shares 22,225,400 shares 22,858,200 shares
Net assets ¥6.1 billion ¥4.7 billion ¥5.3 billion ¥6.6 billion ¥7.2 billion
Total assets ¥6.3 billion ¥4.9 billion ¥5.7 billion ¥7.1 billion ¥7.7 billion
Net assets per share -71,821.21 yen -218.77 yen -353.31 yen 297.44 yen 314.56 yen
Basic earnings (loss) per share -18,900.01 yen -128.99 yen -106.81 yen -49.43 yen 8.44 yen
Diluted earnings per share Could not be retrieved Could not be retrieved Could not be retrieved Could not be retrieved 8.27 yen
Equity-to-asset ratio 97.0% 95.5% 91.9% 93.5% 93.7%
Return on equity Could not be retrieved Could not be retrieved Could not be retrieved Could not be retrieved 2.8%
Net cash provided by (used in) operating activities Could not be retrieved ¥-1.9 billion ¥-0.8 billion ¥-1.3 billion ¥1.1 billion
Net cash provided by (used in) investing activities Could not be retrieved ¥-0.99 million ¥-0.4 billion ¥-67.13 million ¥72.64 million
Net cash provided by (used in) financing activities Could not be retrieved ¥-22.16 million ¥1.8 billion ¥2.1 billion ¥0.4 billion
Cash and cash equivalents Could not be retrieved ¥4.0 billion ¥4.6 billion ¥5.3 billion ¥6.8 billion

Shareholder composition

As of 2025-12-31Disclosed

Share ownership by holder category

16,307 Shareholders
4.03% Foreign holders (total) Industry median 9.03%
73.86% Individuals and others Industry median 55.96%

Heartseed

Unit %Source Annual securities reports

  • Financial institutions0.53%
  • Securities firms1.25%
  • Other corporations20.33%
  • Foreign holders (institutions)3.20%
  • Foreign holders (individuals)0.83%
  • Individuals and others73.86%

Major shareholders

RankShareholderShareholding ratioShares held
1 福田 惠一 13.76% 3,146,000
2 SBI Ventures Two㈱ 9.79% 2,236,800
3 古川 俊治 4.02% 920,000
4 新村 健造 3.69% 842,400
5 ㈱イノベーション企画21 2.84% 650,000
6 ㈱JMDC 2.02% 461,600
7 秋山 琢己 1.93% 441,000
8 五味 大輔 1.53% 350,000
9 SBI AI&Blockchain投資事業有限責任組合 1.16% 264,700
10 ㈱メディパルホールディングス 1.09% 250,000

Research and development expenses and capital expenditure

Source: R&D and capital expenditure sections, annual securities reports · 1 years (FY 2025)Disclosed

¥2.0 billion Research and development
¥28.69 million Capital expenditure

Revenue scale in the same industry

Heartseed

Source Annual securities reports of each company

Pharmaceuticals: 68 companies · revenue · largest first・each company’s latest fiscal year・consolidated (parent-only where no consolidated figures)・Disclosed

Workforce information

Source: Annual Securities Report (Nov 2024 to Dec 2025)Parent-onlyDisclosed

43 Employees (parent only) Industry median 94
45.0 Average age Industry median 44.3
4.9 years Average length of service Industry median 9.6 years
¥8.89 million Average annual salary Industry median ¥8.24 million
People and organisation
70.4¥ million Sales per employee Industry median 38.4¥ million FY ending 12/2025 · parent company only / calculated
¥6.33 million Operating income per employee
2 Average temporary staff

Audit and disclosure information

Annual securities report, year ended 2025-12-31Disclosed

ItemValue
Audit firm EY新日本有限責任監査法人
Audit fees (this year, filing company) ¥27.14 million
Non-audit fees (this year, total) Not applicable
Going concern note Cannot be determined
Accounting standard Japanese GAAP

See the book series →

Sources and methodology

Retrieved disclosed figures

Accounts and values from the annual securities report, by section

Major management indicators (5 years) (16 items)

ItemValueConsolidated / Non-consolidated
Net cash provided by (used in) operating activities ¥1.1 billion Parent only
Net sales ¥3.0 billion Parent only
Net income (loss) ¥0.2 billion Parent only
Net cash provided by (used in) investing activities ¥72.64 million Parent only
Diluted earnings per share 8.27 yen Parent only
Cash and cash equivalents ¥6.8 billion Parent only
Total number of issued shares (common stock) 22,858,200 shares Parent only
Net assets ¥7.2 billion Parent only
Ordinary income (loss) ¥0.3 billion Parent only
Total assets ¥7.7 billion Parent only
Return on equity 2.8% Parent only
Equity-to-asset ratio 93.7% Parent only
Net cash provided by (used in) financing activities ¥0.4 billion Parent only
Capital stock ¥1.3 billion Parent only
Basic earnings (loss) per share 8.44 yen Parent only
Net assets per share 314.56 yen Parent only

Employees (5 items)

ItemValueConsolidated / Non-consolidated
Average length of service (years) 4.9 years Parent only
Average annual salary ¥8.89 million Parent only
Average age (years) 45 years old Parent only
Number of employees 43 people Parent only
Number of employees 43 people Parent only

Other disclosed items (3 items)

ItemValueConsolidated / Non-consolidated
Average number of temporary employees 2 people Parent only
Average number of temporary employees 2 people Parent only
Total return on the share price index 90.1% Parent only

Shares (5 items)

ItemValueConsolidated / Non-consolidated
Number of shares held 9,562,500 shares Consolidated
Number of shares 22,858,200 shares Consolidated
Shareholding ratio 41.8% Consolidated
Number of voting rights 228,367 units Consolidated
Total shareholder return 130.9% Parent only

Research and development (1 items)

ItemValueConsolidated / Non-consolidated
Research and development expenses ¥2.0 billion Consolidated

Property and facilities (1 items)

ItemValueConsolidated / Non-consolidated
Capital expenditures ¥28.69 million Consolidated

Audit (1 items)

ItemValueConsolidated / Non-consolidated
Fees for audit and attestation services - reporting company ¥27.14 million Consolidated

Balance sheet (43 items)

ItemValueConsolidated / Non-consolidated
Other capital surplus ¥2.1 billion Parent only
Lease obligations ¥0.25 million Parent only
Lease assets ¥9.25 million Parent only
Retained earnings ¥-2.6 billion Parent only
Advances received ¥71.49 million Parent only
Prepaid expenses ¥45.91 million Parent only
Advance payments trade ¥26.12 million Parent only
Non-current liabilities ¥0.2 billion Parent only
Non-current assets ¥0.5 billion Parent only
Tools, furniture and fixtures ¥90.21 million Parent only
Tools, furniture and fixtures ¥33.24 million Parent only
Guarantee deposits ¥0.1 billion Parent only
Buildings and accompanying facilities ¥0.5 billion Parent only
Buildings and accompanying facilities net ¥0.4 billion Parent only
Investments and other assets ¥0.1 billion Parent only
Subscription rights to shares ¥4.70 million Parent only
Property, plant and equipment ¥0.4 billion Parent only
Accounts receivable - other ¥3.36 million Parent only
Consumption taxes receivable ¥0.2 billion Parent only
Income taxes payable ¥9.18 million Parent only
Accrued expenses ¥32.62 million Parent only
Accounts payable - other ¥0.2 billion Parent only
Shareholders' equity ¥7.2 billion Parent only
Current liabilities ¥0.3 billion Parent only
Current assets ¥7.1 billion Parent only
Accumulated depreciation and impairment loss ¥-9.25 million Parent only
Accumulated depreciation and impairment loss ¥-56.97 million Parent only
Accumulated depreciation and impairment loss ¥-70.97 million Parent only
Cash and cash equivalents ¥6.8 billion Parent only
Cash and deposits ¥6.8 billion Parent only
Net assets ¥7.2 billion Parent only
Net assets ¥7.2 billion Parent only
Total assets ¥7.7 billion Parent only
Retained earnings brought forward ¥-2.6 billion Parent only
Liabilities ¥0.5 billion Parent only
Liabilities and net assets ¥7.7 billion Parent only
Supplies ¥47.87 million Parent only
Capital surplus ¥8.4 billion Parent only
Legal capital surplus ¥6.4 billion Parent only
Capital stock ¥1.3 billion Parent only
Asset retirement obligations ¥0.2 billion Parent only
Provision for bonuses ¥26.01 million Parent only
Deposits received ¥8.60 million Parent only

Statement of income (32 items)

ItemValueConsolidated / Non-consolidated
Interest income ¥5.92 million Parent only
Operating income ¥0.3 billion Parent only
Non-operating income ¥58.51 million Parent only
Non-operating expenses ¥41.68 million Parent only
Net cash provided by (used in) operating activities ¥1.1 billion Parent only
Gross profit (loss) ¥3.0 billion Parent only
Net sales ¥3.0 billion Parent only
Net income (loss) ¥0.2 billion Parent only
Net income (loss) ¥0.2 billion Parent only
Directors' compensations ¥0.2 billion Parent only
Net cash provided by (used in) investing activities ¥72.64 million Parent only
Interest expenses ¥0.16 million Parent only
Commission fees ¥0.1 billion Parent only
Issuance of new shares ¥0.4 billion Parent only
Income taxes - current ¥0.1 billion Parent only
Income taxes ¥98.38 million Parent only
Income taxes - deferred ¥-3.21 million Parent only
Depreciation ¥7.81 million Parent only
Foreign exchange losses ¥41.52 million Parent only
Effect of exchange rate change on cash and cash equivalents ¥9.92 million Parent only
Net increase (decrease) in cash and cash equivalents ¥1.5 billion Parent only
Research and development expenses ¥2.0 billion Parent only
Research and development expenses ¥2.0 billion Parent only
Income (loss) before income taxes ¥0.3 billion Parent only
Income (loss) before income taxes ¥0.3 billion Parent only
Ordinary income ¥0.3 billion Parent only
Salaries and allowances ¥0.1 billion Parent only
Subsidy income ¥52.00 million Parent only
Net cash provided by (used in) financing activities ¥0.4 billion Parent only
Selling, general and administrative expenses ¥2.8 billion Parent only
Provision for bonuses ¥9.02 million Parent only
Miscellaneous income ¥0.59 million Parent only

Statement of changes in equity (2 items)

ItemValueConsolidated / Non-consolidated
Total changes during the period ¥0.6 billion Parent only
Net changes in items other than shareholders' equity ¥-7.71 million Parent only

Statement of cash flows (26 items)

ItemValueConsolidated / Non-consolidated
Other ¥-39.52 million Parent only
Repayments of lease obligations ¥-5.29 million Parent only
Interest received ¥5.92 million Parent only
Interest expenses paid ¥-0.18 million Parent only
Increase (decrease) in advances received ¥-6.50 million Parent only
Decrease (increase) in prepaid expenses ¥-5.25 million Parent only
Decrease (increase) in advance payments to suppliers ¥16.45 million Parent only
Interest income ¥-5.92 million Parent only
Subtotal ¥1.1 billion Parent only
Interest expenses ¥0.16 million Parent only
Proceeds from collection of lease and guarantee deposits ¥0.1 billion Parent only
Proceeds from exercise of share acquisition rights ¥0.4 billion Parent only
Purchase of property plant and equipment ¥-28.69 million Parent only
(Increase) decrease in accounts receivables other ¥26.70 million Parent only
(Increase)/decrease in consumption tax/value-added tax receivables ¥-45.49 million Parent only
Increase/(decrease) in accounts payable - expenses ¥-4.82 million Parent only
Increase (decrease) in accounts payable-other ¥91.34 million Parent only
Decrease (increase) in inventories ¥38.47 million Parent only
Income taxes refund (paid) ¥-0.1 billion Parent only
Depreciation ¥53.01 million Parent only
Foreign exchange loss (gain) ¥-9.92 million Parent only
Proceeds from subsidy income ¥52.00 million Parent only
Subsidy income ¥-52.00 million Parent only
Payments for asset retirement obligations ¥-5.92 million Parent only
Increase (decrease) in provision for bonuses ¥26.01 million Parent only
Increase (decrease) in deposits ¥-10.31 million Parent only

Accounts unique to this company (1 items)

ItemValueConsolidated / Non-consolidated
Revenue ¥0.8 billion Parent only
Basic indicators
ItemValueConsolidated / Non-consolidatedSource
Net cash provided by (used in) operating activities ¥1.1 billion Parent onlyDisclosed
Number of employees 43 Parent onlyDisclosed
Net assets ¥7.2 billion Parent onlyDisclosed
Net sales ¥3.0 billion Parent onlyDisclosed
Operating income ¥0.3 billion Parent onlyDisclosed
Ordinary income ¥0.3 billion Parent onlyDisclosed
Total assets ¥7.7 billion Parent onlyDisclosed
Operating margin 9.0%Parent onlyCalculated
Net margin Not disclosedNot applicableNot calculated (a required value is not disclosed)
Sales per employee 70383721 yenParent onlyCalculated
Total asset turnover 0.39 timesParent onlyCalculated
Net assets to total assets 93.7%Parent onlyCalculated
How to read the figures, and caveats

Terms

  • Consolidated: the parent company together with the subsidiaries it consolidates
  • Parent-only: the single company that filed the annual securities report
  • Calculated: a disclosed figure put through the formula shown
  • Not disclosed: no such value in the filing (not treated as zero)
  • Not retrieved: a value this page could not extract, including values in the filing that could not be matched. The same item may appear in another table
  • Segment: a business division the company uses in its disclosures
  • Industry median: the middle value among companies in the same industry that disclose the item
  • ★: position when every company is lined up by value (not a judgement of the company)See the formulas
  • Source: document name, period covered, filing date and where it was obtained
  • Tables scroll sideways

Key figures

  • Operating margin 9% Operating income ÷ net sales  = ¥0.3 billion ÷ ¥3.0 billion
    Operating income ÷ net sales. The denominator is Net sales (Parent only, Japanese GAAP).
  • Sales per employee 70,383,721 yen Sales or operating revenue ÷ employees  = ¥3.0 billion ÷ 43 people
    Sales or operating revenue ÷ employees. The denominator is Number of employees (Parent only, Japanese GAAP).
  • Total asset turnover 0.39 times Sales or operating revenue ÷ total assets  = ¥3.0 billion ÷ ¥7.7 billion
    Sales or operating revenue ÷ total assets. The denominator is Total assets (Parent only, Japanese GAAP).
  • Net assets to total assets 93.7% Net assets ÷ total assets  = ¥7.2 billion ÷ ¥7.7 billion
    Net assets ÷ total assets. The denominator is Total assets (Parent only, Japanese GAAP).

Company details

  • Representative President, Representative Director, gBizINFO

Amounts by account

  • Totals and their component lines together; consolidated and parent-only figures mixed (right-hand column)

Selling, general and administrative expenses

  • Breakdown of selling, general and administrative expenses (costs of selling and running the company). Cost of sales not included
  • Each item: already inside the SG&A total (not added to it)

Finance

  • Net assets to total assets Net assets ÷ total assets
  • Net assets per share Parent only
  • Total assets Parent only

Capital allocation

  • ★: position when all companies are sorted by value and cut into fifths (a position, not a rating). The five items with ★: only where both numerator and denominator are available on a consolidated basisSee the formulas
  • Cash conversion Net cash provided by (used in) operating activities ÷ operating income

Year-on-year comparison

  • Year on year: calculated only where the item, reporting range and accounting standard match and the periods are consecutive
  • Comparison basis not confirmed: periods with a change of accounting standard or reporting range, a moved fiscal year end, or an unconfirmed period
  • ◆: a period where revenue moved 20% or more from the prior year, profit as a share of revenue moved 2.0 percentage points or more, or profit or loss changed sign. Item used named in the table and list. Not a ranking of companies

Earnings and net assets per share over time

  • Earnings per share = net profit ÷ shares; net assets per share = net assets ÷ shares. Disclosed values from the key financial indicators of the annual securities report. No share prices used

Share ownership by holder category

  • Source: ownership table, annual securities report. Percentages as disclosed, calculated on trading units (some companies do not total exactly 100%). Foreign holders (total): institutions and individuals combined. “Individuals and others”: a register category (not necessarily the share actually held by individuals). Industry median: the middle value among companies in Pharmaceuticals that disclose the item (industries with at least 5 companies only).

Major shareholders

  • Source: major shareholders table, annual securities report. Trust bank holdings as written (whose trust is not disclosed)

Research and development expenses and capital expenditure

  • Research and development: total in the R&D section of the annual securities report. Capital expenditure: this year’s actual spending in the capital expenditure overview (not a plan). Years: only those available in the annual securities reports on hand (one to four per company); no row for other years.

Revenue scale in the same industry

  • Revenue (disclosed values) of companies in the same industry, using the same grouping as the industry pages. Only the top three and the two companies either side of this one. Bar length relative to the largest company (100). An order of size, not a ranking of quality

Workforce information

  • All four: the reporting company (parent-only), as disclosed in the employee section of the annual securities report. Industry median: the middle value among companies in Pharmaceuticals that disclose the item (industries with at least 5 companies only).

People and organisation

  • Sales per employee Net sales (or operating revenue) ÷ employees
  • Operating income per employee Operating income ÷ employees
  • Average temporary staff Parent only, average headcount other than regular employees

Audit and disclosure information

  • Whether there is a going concern note (the accounting assumption that a company will continue operating), and audit information
  • Audit firm, audit fees, going concern note and accounting standard: facts written in the latest annual securities report and the audit report filed with it (not a judgement of the company). Going concern note: “note” when the note text is present, “not applicable” when the report states nothing to report, “cannot be determined” when neither appears. Note text not reproduced. Amended filings not shown (annual securities reports only)

Data sources and calculation methods

Primary source: the annual securities report of Heartseed株式会社 on EDINET, the FSA’s disclosure system (free to read)
Corporate number: 4011001108455 / Accounting standard: Japanese GAAP

  • Amounts: machine transcription of EDINET XBRL (no manual re-keying). Long narrative notes are text and not in the account list. Identifiers: machine transcription of the EDINET code list (retrieved 2026-08-22)
  • ★: position of the value calculated from disclosed figures among the 4,240 companies on this site, on a five-step scale. Not a judgement of the company. No forecasts usedThe formulas and how they are counted
  • No rank: net assets as a share of total assets, cash conversion and revenue per employee (size alone does not show quality). Industry median shown for comparison. Cash conversion of 100%: operating cash flow equal to operating profit
  • Profit-and-loss chart: only where “sales − cost of sales − SG&A = operating income” holds between disclosed values. Cost breakdown: the six largest SG&A items
  • Trend charts: key financial indicators of the annual securities report. Amounts in billions of yen (dividend per share in yen). Long-run chart joins reports filed in different years (newer report for overlapping years). Some items stop part-way after a change of accounting standard. A stock split changes the weight of one share. Consolidated and parent-only in separate tables
  • Revenue scale in the same industry: bars of revenue (disclosed values) of companies in the same industry grouping as the industry pages, largest first. Only the top three and the two companies either side of this one. Each company’s latest fiscal year. An order of size, not a ranking of quality or an investment view
  • Share prices: not published (no data source allows redistribution). No share-price-based indicators (such as the price earnings ratio) and no extension of past growth into the future
  • Average age, average length of service and average annual salary: the reporting company alone (the parent). At a holding company, a small head-office staff. Payout ratio (basic facts): dividend per share ÷ consolidated earnings per share, calculated here (the payout ratio in the annual securities report is the reporting company’s figure, on a different basis). Representative and founding date: gBizINFO (Ministry of Economy, Trade and Industry), some companies only
  • “Retrieved disclosed figures”: every value readable as a number from the annual securities report. Company-wide values only (no segment or other breakdowns)
  • Segment table: machine transcription of the segment information in the annual securities report. Business names as labelled by the company in its XBRL. No table where segment sales differ from the disclosed total by more than 1%. Adjustments, corporate, eliminations and “other” left out of the table and the share denominator, as they are not businesses
  • Breakdowns of amounts, not diagrams of how the business works. Who pays whom, and for what, is not in the disclosed figures; no lines drawn from guesswork